简介:摘要目的精确评估乳腺癌保乳术后辅助质子放疗患者自由呼吸对质子束流末端截止位置的影响。方法选取20例乳腺癌保乳术后质子放疗患者,照射结束后10 min左右进行PET-CT扫描,图像在Raystation RV工作站上进行感兴趣区的确定和采样线的抽提,计算同一空间位置的预测感生放射性和由PET采集得到的真实感生放射性之间的空间差异ΔR50,将每对采样线的深度误差值ΔR50进行二维转化和束流视野投影。结果20例乳腺癌患者中位随访时间22个月,随访期内未观察到放射性肺炎的发生。20例患者进行了21例次验证,结果显示均匀分布的主视野、副视野的深度误差分别为(-0.75±1.89)mm、(-0.82±2.06)mm,序贯治疗的主视野、副视野深度误差分别为(1.81±1.87)mm、(1.32±1.74)mm,同步加量的主视野、副视野的深度误差分别为(-1.47±1.44)mm、(-1.48±2.11)mm。结论离线PET-CT在体生物验证结果显示,乳腺癌质子射线的束流末端截止误差在3 mm内,满足临床与物理师对乳腺癌治疗的精度要求。
简介:AbstractThe aim of this paper is to discuss the risk of recurrence in patients with differentiated thyroid cancer and emphasize the importance of risk-group stratification, early recurrence identification and application of new imaging modalities, what is the PET-CT. Moreover, follow-up of patients with thyroid carcinoma should be carried out by specialized teams throughout life. Therefore, interdisciplinary case discussions in tumor conferences may improve the use of multimodal therapy especially in patients with poorly differentiated thyroid carcinomas. After baseline follow-up, if there is a suspicion of thyroid carcinoma, early PET-CT should be used for early detection and appropriate planning. Fortunately, due to the good localization possibility, the PET-CT enables a focused surgical procedure with avoidance of an unnecessary tumor search and thereby a reduction of the risk of injury of neighboring structures which is a concern with reoperative neck surgery.
简介:【摘要】目的:分析螺旋CT、PET-CT扫描诊断肺癌及淋巴结转移的临床有效性。方法:随机选取2018年3月~2020年12月期间在我院进行治疗的肺癌并疑似淋巴结转移患者55例做为研究对象,所有患者于就诊后1周内均进行螺旋CT以及PET-CT检查,并且均通过手术病理诊断,以手术病理诊断做为标准,对比螺旋CT和PET-CT检查对于肺癌及淋巴结转移的检出率。结果:与手术病理结果对比螺旋CT检出的准确率为80%,PET-CT检出的准确率为96.72%。P<0.05,有统计学意义。结论:螺旋CT与PET-CT相较而言,PET-CT的诊断准确率更高,临床上可以根据患者的实际情况采取相应的检查方法。