简介：【 摘要 】 目的： 探究 20 例肺心病合并冠心病的临床疗效 , 分析发病情况。 方法： 选取 2018 年 3 月 -2019 年 3 月在我院开展肺心病合并冠心病治疗的 20 例患者为研究对象，对临床资料展开回顾性分析，随机分为对照组（ n=10 ）及研究组（ n=10 ），

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简介：摘要以我院20例老年冠心病患者的早期临床护理干预为案例，说明老年冠心病患者的早期临床护理方法。本次研究说明了对于老年冠心病患者要从饮食、运动、环境、评估、心理、药物这六个方面进行护理。从护理的结果来看，20例老年冠心病患者的病症减轻，生活质量明显提高。

简介：ABCA1基因C69T多态与冠心病关联研究；大动脉脉压与冠状动脉病变严重程度的相关性研究；肺炎衣原体感染与2型糖尿病患者冠状动脉粥样硬化的相关性；血清尿酸水平与冠心病的关系；^99Tcm-MIBI对判断冠心病患者PTCA术后疗效的价值。

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简介：AbstractBackground:High levels of plasma homocysteine occur almost uniformly in patients with end-stage renal disease (ESRD). IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis and a common cause of ESRD in young adults. Here, we aimed to detect whether homocysteine was elevated and associated with clinical-pathologic manifestations of IgAN patients and tested its causal effects using a two-sample Mendelian randomization (MR) approach.Methods:For observational analysis, 108 IgAN patients, 30 lupus nephritis (LN) patients, 50 minimal change disease (MCD) patients, and 206 healthy controls were recruited from April 2014 to April 2015. Their plasma homocysteine was measured and clinical-pathologic manifestations were collected from medical records. For MR analysis, we further included 1686 IgAN patients. The missense variant methylenetetrahydrofolate reductase C677T (rs1801133) was selected as an instrument, which was genotyped by TaqMan allele discrimination assays.Results:Majority of IgAN patients (93.52%, 101/108) showed elevated levels of plasma homocysteine (>10 μmol/L). Plasma homocysteine in IgAN patients was significantly higher than that in MCD patients (median: 18.32 vs. 11.15 μmol/L, Z = －5.29, P < 0.01) and in healthy controls (median: 18.32 vs. 10.00 μmol/L, Z = －8.76, P < 0.01), but comparable with those in LN patients (median: 18.32 L vs. 14.50 μmol/L, Z = －1.32, P = 0.19). Significant differences were observed in sub-groups of IgAN patients according to quartiles of plasma homocysteine for male ratio (22.22% vs. 51.85% vs. 70.37% vs. 70.37%, χ2 = 14.29, P < 0.01), serum creatinine (median: 77.00 vs. 100.00 vs. 129.00 vs. 150.00 μmol/L, χ2 = 34.06, P < 0.01), estimated glomerular filtration rate (median: 100.52 vs. 74.23 vs. 52.68 vs. 42.67 mL·min－1·1.73 m－2, χ2 = 21.75, P < 0.01), systolic blood pressure (median: 120.00 vs. 120.00 vs. 125.00 vs. 130.00 mmHg, χ2 = 2.97, P = 0.05), diastolic blood pressure (median 80.00 vs. 75.00 vs. 80.00 vs. 81.00 mmHg, χ2 = 11.47, P < 0.01), and pathologic tubular atrophy and interstitial fibrosis (T) (T0/T1/T2: 62.96%/33.33%/3.70% vs. 29.63%/40.74%/29.63% vs. 24.00%/48.00%/28.00% vs. 14.81%/37.04%/48.15%, χ2 = 17.66, P < 0.01). The coefficient of each rs1801133-T allele on homocysteine levels after controlling age and sex was 7.12 (P < 0.01). MR estimates showed causal positive effects of homocysteine on serum creatine (β = 0.76, P = 0.02), systolic blood pressure (β = 0.26, P = 0.02), diastolic blood pressure (β = 0.20, P = 0.01), and pathologic T lesion (β = 0.01, P = 0.01) in IgAN.Conclusions:By observational and MR analyses, consistent results were observed for associations of plasma homocysteine with serum creatinine, blood pressures, and pathologic T lesion in IgAN patients.

简介：题中数字从简,说全了应该是19××年变为2000年。19××年的最初一年是1900年,东土化就成为清光绪二十六年庚子。稍知旧事的人都记得,这是义和团扶清灭洋、八国联军占领北京、清统治者西太后带着光绪皇帝等逃往西安的那一年。思昔抚今,只是一个世纪,变化真是太大了。语云,'一年之计在于春',又商业传统,一年之底要结一年之账,所以由几个月之前起我就不断接到命题作文之命,让谈谈回顾得什么教训,眼转回来看将来有什么希望。一部十七史,从何说起?记得先推后就,还真写了一篇千字文。用制义法,大题反而要收敛,于是抓住一个总的

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简介：摘要冠心病是一种最常见的心脏病，是指因冠状动脉狭窄，供血不足而引起的心肌机能障碍和器质性病变，故又称缺血性心脏病，症状表现胸腔中央发生一种压榨性的疼痛，并可迁延至颈、颔、手臂、后背及胃部，发作的其他可能症状有眩晕、气促、出汗、寒颤、恶心及昏厥，严重患者可能因为心力衰竭而死亡。

简介：过去认为急性心肌梗死是由血栓和血管壁硬化斑块破裂后出血引起的。而新近的研究证实，血栓和血管壁硬化斑块破裂后出血，不会使血管突然阻塞。医生们发现，所有急性心肌梗死患者在发病前的一周内，就已经存在血管壁硬化斑块破裂和血栓形成，血管直径的70％已经被堵塞，在此基础上才会导致心肌梗死的急性发作。此项研究的重要意义在于说明了急性心肌梗死前，

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