简介：Anewmethodofcontrastenhancementisproposedinthepaperusingmultiscaleedgerepresentationofimages,andisappliedtothefieldofCTmedicalimageprocessing.ComparingtothetraditionalWindowtechnique,ourmethodisadaptiveandmeetsthedemandofradiologyclinicsmorebetter.TheclinicalexperimentresultsshowthepracticalityandthepotentialappliedvalueofourmethodinthefieldofCTmedicalimagescontrastenhancement.

简介：目的：探讨脑电地形图与CT在常见神经系统疾病中的对比应用。方法：509例患者进行了脑电地形图和CT检查。结果：在509例患者中脑电地形图和脑CT显示了不同的改变。结论：脑电地形图和脑CT在常见神经系统疾病的诊断中，各具有其优点和不足。脑电地形图在常见神经系统疾病的临床应用中有重要价值。

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简介：Nanotechnologyprovidesvariousnanomaterialswithtremendousfunctionalitiesforcancerdiagnosticsandtherapeutics.Recently,theranosticshasbeendevelopedasanalternativestrategyforefficientcancertreatmentthroughcombinationofimagingdiagnosisandtherapeuticinterventionsundertheguidanceofdiagnosticresults.Ultrasound(US)imagingshowsuniqueadvantageswithexcellentfeaturesofreal-timeimaging,lowcost,highsafetyandportability,makingUScontrastagents(UCAs)anidealplatformforconstructionofcancertheranosticagents.ThisreviewfocusesonthedevelopmentofnanomaterialsincorporatedmultifunctionalUCAsservingastheranosticagentsforcancerdiagnosticsandtherapeutics,viaconjugationofsuperparamagneticironoxidenanoparticles(SPIOs),CuSnanoparticles,DNA,siRNA,goldnanoparticles(GNPs),goldnanorods(GNRs),goldnanoshell(GNS),grapheneoxides(GOs),polypyrrole(PPy)nanocapsules,Prussianblue(PB)nanoparticlesandsoontodifferenttypesofUCAs.Thecancertreatmentcouldbemoreeffectivelyandaccuratelycarriedoutundertheguidanceandmonitoringwiththehelpoftheachievedtheranosticagents.Furthermore,nanomaterialsincorporatedtheranosticagentsbasedonUCAscanbedesignedandconstructedbydemandforpersonalizedandaccuratetreatmentofcancer,demonstratingtheirgreatpotentialtoaddressthechallengesofcancerheterogeneityandadaptation,whichcanprovidealternativestrategiesforcancerdiagnosisandtherapeutics.

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简介：目的：探讨脑电地形图与脑CT在脑感染性疾病诊断中的应用价值。方法：脑电地形图和脑CT在99例患有脑感染性疾病患者中被检查了并且进行了对比。结果：在疾病的定性和定位诊断中,脑电地形图和脑CT是一致的。但是,在阳性率方面,散发性病毒性脑炎在脑电地形图中94例是阳性,而在CT中只56例是阳性。结论：脑电地形图在脑感染性疾病的诊断中有重要应用价值。

简介：Objective:ToexploreleveldiagnosisonCTandBAincerebrovasculardiseases.Method:CTandBAwereexaminedin53patientswithcerebrovasculardiseasesandcomparedinleveldiagnosis.Result:ThesidesonleveldiagonsisofCTandBAwereidentical.TherangofdiseaseswaslargerinBAthanthatinCT.Conclusion:BAcanhelpleveldiagnosisincerebrovasculardiseases.TheleveldiagnosisofBAandCTwerebasicallyidentical.

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简介：Basedonthesymptomchecklist90,EPQscaleandthesimplifiedcopingstylequestionaire,theauthormadearelativestudyonpsychologicalhealth,personalitycharacterandcopingstyleof267prisonguardofpolicebureauinXi'ancity.Thestudyshowsthis:①Thementalhealth,personalitycharacterandcopingstylecouldbeeffectedbymanyfactors,suchasgender,age,educationalbackground,income,origin,satisfactorydegreeofworkingenviromentandsomeothers.Thementalhealth,personalitycharacterandcopingstylecouldeffecteachother.②Thepsychologicalhealthstateof267prisonguardismuchworsethanthatofdomesticcommonpeople.③Thepersonalitycharacterof267prisonguardshowsmuchhigherhostilityandlowernervousthanthatofdomesticcommonpeople.④Thecopingstyleof267prisonguardoftentakepositivecopingstyles.⑤Psycholggicalhealth,personalitycharacterandcopingstyleofprisonguardarecloselyrelated.

简介：ObjectivesTostudythecharacteristicofpulmonaryembolism(PE)incontrast-enhancedCT.MethodsTheradiologicalfeaturesweredescribedin20patientswithlobarandproximalPEdiagnosedwithaToshibaXpress/SXCTscanneraftercontrastmaterialwasadministrated.ResultsTherewere7casesofpulmonaryembolism(PE)secondarytolowerlimbdeepveinthrombosis(DVT),ofwhich2caseswererelatedtosaunabath.Wegroupedthecasesaccordingtotheirextensivenessofembolism:mild,moderate,severe,orcompleteembolism.Mildembolism:theembolioccupiedlessthan30%,oftheinnerdiameterofpulmonaryartery(PA).Medianembolism:theembolioccupied30~50%ofthePAdiameter.Severeembolism:theembolioccupiedoverhalfofthePA(50%),buttherewerecontrastflow.Completedembolism:therewasnocontrastfoundaroundtheemboli.ThedirectsignofPEwasafillingdefectornoopacificationintheaffectedbranchofpulmonaryartery(PA).Therewere9othersecondarysigns:①widenPA,②enlargedrightventricleandtherightatrium,③increasedtranslucencyofthelunganddecreasedbronchovascularshadows,④shrunkenpulmonaryveinslikeddriedrattan,⑤decreasedleftatriumandtheleftventriclesize,⑥shiftingofinterventricularseptumtotheleftandposteriordirection,⑦Thelaterallungparenchymademonstratedinatriangularshape,⑧pleuraleffusionand⑨pericardiacleeffusion.ConclusionsThediagnosisofPEwasrevealedby10radiologicalsignsbycontrast-enhancedCT:Withfullunderstandingofthepathophysiologicalbasisofthese10signs:correctdiagnosisofpulmonaryembolismcanbemade.PEiscommonlycausedbylowerlimb.Andsaunabathisoneofthemainpredisposingcauses.

简介：Tosutdythemechanicalpropertiesandtheclinicalresultsofminimum-contactplateinthetreatmentoffractures.Methods:Four-pointbendingandtorsiontestswereconductedtocomparethenewminimumcontactplate(MCP)withdynamiccompressionplate(DCP)andlimitedcontactdynamiccompressionplate(LC-DCP).Thefracturehealingtimeandgrowthofhonycalluswereobservedin29casesoflongbonefracturefixedwithMCPtoevaluatetheadvantagesofthiskindofplate.Results:The29patientswhounderwentMCPwerefollowedupfrom6to14months.Theaveragehealingtimeforfemoral,tibialandhumeralfractureswas12,13and10weeks,respectively.Allfractureswerehealed.Nodisplacementoffracture,screwpullout,deformationorhreakoftheplatewerefound.Conclusions:ThebendingstiffnessofMCPissignificantlygreaterthanthatofDCPandLC-DCP(P<0.05).MCPcanprotecttheperiostealhloodsupplyagainstavascularosseousnecrosisandacceleratehonehealing.Itisakindofreliableandeffectiveplateintreatmentoffractures.

简介：ObjectivesToinvestigateserumconcentrationofprocollagentypeIcarboxyterminalpeptide(PIP),typeⅢaminopeptide(PⅢP)andtypeIcollagentelopeptide(ICTP)inessentialhypertension(EH).MethodsSerumlevelsofPIP,PⅢPandICTPin42EHpatientsand30healthycontrolweremeasuredbyradioimmunoassays.ResultsInEHpatients,serumconcentrationofPIP,PⅢPwassignificantlyhigherthanthatin30healthycontrol.AlthoughEHpatientsdidtendtoexhibitahigherserumICTPconcentrationthannormalcontrolsubjects,thedifferencewasnotstatisticallysignificant.EHpatientswithleftventricularhypertrophyexhibitedhighervaluesofPIP(P<0.05)andlowervaluesofICTP(P<0.05)thanEHpatientswithoutleftventricularhypertrophy.NosignificantdifferencewasnotedbetweentheserumPⅢPoftheEHpatientswithandwithoutleftventricularhypertrophy(P>0.05).ConclusionsTheresultssuggestthatPIPandPⅢParesensitiveserummarkersofmyocardialcollagensynthesis.Myocardialfibrosismaybeduetotheexcessivesynthesisandinsufficientdegradationofcollagen.PIP,PⅢPandICTPmaybeindirectmarkersofmyocardialfibrosis.

简介：Propagation-basedphase-contrastimagingwassimulatedbasedonparaxialFresnel-Kirchoffdiffractionintegralandsphericalwaveillumination.Underadevelopedmicro-CTsystemparameters,theeffectsoffocal-spotsizeandimaginggeometryonphase-contrastimaginghavebeeninvestigatedusinga2-mm-thicknesspolystyreneedgephantom.Anequivalentmono-energywasusedtosubstitutethepolychromaticspectrumofthemicro-focusX-raysource.Toconsidereffectsoffocal-spotsizeanddetectorresolution,theobtainedphase-contrastimagewithanidealpointsourcewasconvolvedwithsourceintensitydistributionandpointspreadfunctionofdetector.Simulationsshowreasonableinfluencesofthetwoparameterswhichareingoodagreementwithexperimentalresults.

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简介：AbstractMolecular imaging is of great significance for early diagnosis and timely treatment of cancer and disease, as well as basic medical and biological research. As personalized cancer treatment has become increasingly popular, the demand for more advanced imaging technologies has also significantly increased. Taking advantage of differences between the tumor microenvironment and normal tissue cells, tumor microenvironment-responsive or "turn-on" contrast agents have a higher signal-to-noise ratio and lower background interference compared with "turn-off" probes, which can remarkably improve the performance of tumor diagnostics. Thus, tumor microenvironment-responsive contrast agents can not only detect changes in the tumor microenvironment, but also have important significance for tumor diagnosis, prediction of invasion potential, evaluation of treatment effectiveness, planning of therapeutic regimens, and tumor prognosis. Herein, this review focuses on recent research progress of tumor microenvironment-responsive intelligent probes, and highlights future research directions of tumor microenvironment-responsive contrast agents for precision diagnostics.

简介：AbstractPrenatal micronutrients in pregnant women’s diets, including supplements, have an essential role in fetal brain development and may reduce the risk of mental disorders in offspring. Folic acid, vitamin D, omega-3 fatty acids, and choline have been investigated for this purpose. Folic acid supplementation throughout pregnancy has well-established positive effects. Vitamin D, administered to the mother before birth or to the newborn, has also been shown to reduce the risk of neurodevelopmental disorders. Omega-3 fatty acids during pregnancy have a more uncertain role, with recent trials questioning a beneficial effect on cognition and attention deficit disorder, despite positive effects on prematurity and neonatal wheezing prevention. Choline supplementation is associated with positive effects on cognition and behavior, including early behaviors associated with the development of autism and schizophrenia. There is no experience yet with COVID-19, but adverse effects on fetal brain development of most common coronaviruses are mitigated by higher choline levels. Maternal dietary supplementation of nutrients is a benign and inexpensive intervention in pregnancy to prevent life-long disability from mental illness. Use of dietary supplements in poorer, rural areas of China is below recommendations. Physicians, midwives, and public health officials in China can promote prenatal nutrient supplementation to reduce the future burden of mental illnesses that might be prevented before birth.

简介：瞄准：评估诊断精确性，敏感，在检测颜色的本地复发的提高对比的计算tomographiccolonography的特性表面的癌症。方法：从2000年1月到2004年12月，434个病人在以后潜在地药品为侵略颜色的切除术表面的癌症被跟随在上面为从20～55瞬间的经期。为复发显示出充分临床的证据的434个病人中的八十个在最后后续期间渲染表面的癌症在这研究被注册。每个病人在一样的天经历了提高对比的计算tomographiccolonography和结肠镜检查。任何损害，活体检视，在colonoscopic期间鉴别检查，立即的复杂并发症和过程的持续时间被记录。提高对比的计算tomographiccolonography的结果被结肠镜检查，发现的surgical，和临床的后续比作那些评估。结果：提高对比的计算tomographiccolonography在检测本地周期性的颜色有100%，83%的特性和94%的全面精确性的敏感表面的癌症。结论：常规结肠镜检查和提高对比的tomographiccolonography能在检测颜色的本地复发补充对方表面的癌症。

简介：目的：探讨70岁以上老年人脑卒中患者的心电图、CT和临床表现的特点及其预防和治疗方法。方法：100例患者的心电图、CT和临床表现被分析了。结果：这些患者的心电图和CT改变以及临床表现是各不相同的。结论：70岁以上老年人的脑卒中患者是具有一定特点的。

简介：Inthisarticle,wepresentanalternativederivationforBronnikov’sreconstructionalgorithminX-rayphasecontrasttomographywithholographicmeasurements.Atwo-stepmethodwasusedinthealternativederivation.ThephaseshiftinducedbytheobjectwasobtainedbyFouriertransformandtherealpartofthecomplexrefractiveindexoftheobjectwasretrievedbyapplyingtheconventionalfilteredbackprojectionmethod.Thealternativederivationprovidesaneasierwaytounderstandthereconstructionformula.

简介：X光检查同轴的阶段对比成像微弱地启用吸收标本与高分辨率和定义成功地被想象。在这篇论文，我们使用计算机模拟方法分析每个参数怎么影响图象的质量。它能避免在实验期间浪费不必要的时间和材料得到理想的图象。