学科分类
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1 个结果
  • 简介:AnargonatmosphericpressureplasmajetwasemployedtotreatL929murinefibroblastsculturedinvitro.Experimentalresultsshowedthat,comparedwiththecontrolcells,thetreatmentoffibroblastswith15sofplasmaledtoasignificantincreaseofcellviabilityandcollagensynthesis,whilethetreatmentof25splasmaresultedinaremarkabledecrease.Explorationofrelatedmechanismssuggestedthatcoldplasmacouldup-regulateCyclinD1geneexpressionanddown-regulatep27geneexpressionatalowdose,whileitcoulddown-regulateCyclinD1expressionandup-regulatep27expressionatahigherdose,thusalteringthecellcycleprogression,andthenaffectingcellviabilityandcollagensynthesisoffibroblasts.

  • 标签: 成纤维细胞 冷等离子体 细胞活力 胶原合成 小鼠 P27基因