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简介:在分数之间的关系在风险分数系统(RSS)获得了的AIMTo分析与渗透keratoplasty(PKP)由希克斯等求婚了在1y的接枝失败手术后地并且在在有PKP接枝失败的风险的RSS的每个因素之中使用univariate和multivariateanalysis.METHODSThe有的回顾的队学习152从152个病人的PKP。十八个盒子由于主要失败(10个盒子)从我们的学习被排除,不完全的医药笔记(5个盒子)和后续不到1y(3个盒子)。我们从134个病人包括了134PKP在外科手术前的风险分数成层。枪兵系数在1y为在获得的分数和失败的风险之间的关系被计算。Univariate和multivariate分析为在1y.RESULTSSpearman系数在接枝失败上在RSS包括的每个单个风险因素的影响被计算在在RSS和接枝失败的分数之间的显示出的统计上重要的关联(P<0.05)。Multivariate逻辑回归分析没显示出统计上重要的关系(P>0.05)在有接枝失败的诊断和透镜地位之间。在因素学习了的另外的风险和接枝失败之间的关系是重要的(P<0.05),尽管以前的接枝的结果和接枝失败是不可靠的。这样,任何一个都没我们的病人有以前的输血它没有impact.CONCLUSIONAftermultivariate分析技术的申请,一些风险因素不在1y在接枝失败上显示出期望的影响。
简介:·AIM:Toinvestigatethepossibleeffectsofintracameralbevacizumabonoxidativestressparametersandapoptosisincornealtissue.·METHODS:Intotal,30ratswereassignedrandomlyintothefollowingthreegroupsof10ratseach:ashamgroup(Group1;n=10),acontrolgroup[Group2;balancedsaltsolution(BSS)wasadministeredat0.01mL;n=10],andatreatmentgroup(Group3;bevacizumabwasadministeredat0.25mg/0.01mL;n=10).Thetotalantioxidantstatus(TAS)andthetotaloxidantstatus(TOS)inthecornealtissueandbloodsamplesweremeasured,andtheoxidativestressindex(OSI)wascalculated.Additionally,cornealtissuehistopathologywasevaluatedforcaspase-3and8stainingandapoptoticactivity.·RESULTS:Inthebloodsamples,theTAS,TOS,andOSIlevelswerenotsignificantlydifferent(allP>0.05).Comparedwiththeshamandcontrolgroups,theTOSandOSIlevelsinthecornealtissuesweresignificantlydifferentinthebevacizumabgroup(allP<0.05).Nostatisticallysignificantdifferenceswereobservedbetweentheshamandcontrolgroups(allP>0.05).However,comparedwiththeshamandcontrolgroups,greaterimmunohistochemicalstainingforcaspases-3and8andanelevatedlevelofapoptoticactivitywereobservedinthebevacizumabgroup.·CONCLUSION:Thisstudyrevealedthatintracameralbevacizumabinjectionsseemedtobesystemicallysafebutmayhaveelicitedlocaltoxiceffectsinthecornealtissue,asindicatedbytheoxidativestressparametersandhistopathologicalevaluations.
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