简介:ObjectiveBloodoxygenationlevel-dependentfunctionalmagneticresonanceimaging(BOLD-fMRI)wasusedtostudyactivationsignalsinthebraincortexevokedbytonestimulationinpatientswithtinnitusforitspotentialutilityasanobjectiveindicatoroftinnitus.MethodsBOLD-fMRIexaminationwasconductedin7patientswithchronictinnitusand15controlsubjects.Theactivationsignalinthebraincortexwasrecorded.ResultsSignificantactivationwasfoundintemporallobeincontrolsubjects,withgreatersignalvolumeandintensityonthecontralateralthanipsilateralauditorycortex(P<0.01).However,therewasnodiscernablepatternsintheanatomicallocation,volumeandintensityofcorticalactivationsignalsinpatientswithchronictinnitus.ConclusionsPatientswithchronictinnitusmayhaveabnormalneuralactivitiesintheauditorycortex.