简介：Anacousticbasedinstrument,theABSAcousticBubbleSpectrometer??(ABS),wasinvestigatedforthedetectionandquantificationofbubblesinbiologicalmedia.Theseincludeviscoelasticmedia(blood),materialsofvaryingdensity(boneintissue),non-homogenousdistributionofbubbles(intravenousbubblyflow),andbubblesmigratingintissue(decompressionsickness,DCS).TheperformanceoftheABSwasdemonstratedinaseriesoflaboratoryexperiments.Validationofthecodewasperformedusingaviscoelasticpolymersolution,Polyox,inwhichthebubblesizedistributionandvoidfractionweredeterminedbyABSmeasurementsandwithimageanalysisofhighspeedvideos.ThesetestsshowedthattheaccuracyoftheABSwasnotsignificantlyaffectedbyviscoelasticityforbubblessmallerthan200microns.TheABSdetectionandmeasurementofnon-homogenousbubbledistributionswasdemonstratedusingabubblyflowthroughasimulatedveinsurroundedbytissue.Thescatterofacousticsignalsduetobonesintheacousticpathwaywasalsoinvestigated.Thesein-vitroexperimentsweredoneusingmeat(beef)asatissuesimulant.Decompressionexperimentsweredoneusingbeefmeatwhichwasheldunderwaterathighpressure(9.9atm)thenrapidlydecompressed.Bubblesizedistributionsandvoidfractioncalculationsintheseexperimentswerethenvalidatedusingimageanalysisofhighspeedvideo.Inaddition,preliminaryexperimentswereperformedwiththeUSNavyMedicalResearchCenter,demonstratingtheutilityofthemodifiedABSsystemindetectingtheevolutionofbubblesinswineundergoingdecompressionsickness(DCS).TheseresultsindicatethattheABSmaybeusedtodetectandquantifytheevolutionofbubblesin-vivoandaidinthemonitoringofDCS.

简介：Theacousticperformanceofthestructureformeasuringcavitationnoiseistheoreticallyanalysed,andtwojudgingcriteriaoftheacousticperformanceofSTW（soundtransmissionwindow）arepresentedinthispaper.OneisofimpedancematchingbetweenworkingliquidandSTW:ρ1C1=ρ2C2.Theotherisofmaximumfrequency（orminimumwavelength）ofcavitationnoisespectrum:fmax≤c/60D(orλmin/D≥60).Ifeitherofthecriteriaismetreliablemeasuredresultsofcavitationnoisewillbeobtained.Thetheoreticalresultsareverifiedthroughexperi-ments.Accordingtothecriteria,thepaperanalysestheacousticperformanceofroutinelyusedplexiglassSTW.Theresultsshowthatintheresearchofclearwatercavitationtheimpedanceratio,2.18,doesnotsatisfyρ1C1=ρ2C2,andfmax≤C/60Dhardlyholdsforactualcavitationnoisespectrum.Therefore,plexiglassSTWisnotgoodenoughforsoundtransmission.Fromthispointofview,polyethyleneisbettersoundtransmissionmaterialthanplexi-glass.