简介:Self-assemblednanostructuresoflipidsandnanoparticlesholdgreatpromiseforapplicationsinsuchfieldsasnanomedicine.Thispaperusestheself-consistentfieldtheorytoinvestigatetheself-assemblybehavioroflipidmoleculesandnanoparticleswithdifferentshapesinanaqueoussolution.Itisfoundthatthelipidmoleculescanformmonolayeredandbilayerednanostructuresaroundthenanoparticleswithdifferentshapes(e.g.,triangular,square,hexagonalandoctangular).Withdecreasingthesizeofnanoparticlesorincreasingthenumberofpolygonedges,theshapeoflipidlayerswillapproachanapproximatelysphericalshape.Thesefindingsmayhelptopredictanddesignnoveldrugdeliverynanocarriers.