简介:Lactivicin,anovelinhibitorofbacterialcellwallsynthesis,wasisolatedfromtheculturefil-tratesofmicroorganismYK-258andYK-422.Itexhibitsbiologicalactivitiessimilartothoseoftheβ-lactamantibiotics,althoughitdoesnothaveaβ-lactamringinitsmolecule.Sincethediscoveryoflactivicin,hundredsofitsderivativeshavebeensynthesized.Most