简介:Accumulatingevidencefromepidemiologicalandexperimentalstudiesindicatethatobesity,anditsrelatedmetabolicconsequencesofinsulinresistanceandtype2diabetes,areassociatedwithacceleratedcognitivedecline(Yatesetal.,2012).Theetiologyofneurodegenerationinobesityisundoubtedlycomplex,withvascular,metabolic,inflammatory,andstructuralchangesalllikelytoplayarole(Yatesetal.,