简介:摘要甲基苯丙胺(methamphetamine,MA)具有神经毒性大、心理依赖更强的特点,目前MA依赖尚缺乏有效干预措施。本课题组针对MA依赖的脑病理损害及临床特征,开发构建虚拟现实渴求评估系统,认知、冲动损害评估,态势分析法分析社会心理因素等新型多维度评估指标;并研发计算机化认知康复训练技术、针对降低心理渴求的精准化神经调控干预、正念防复吸和音乐治疗技术及基于移动医疗技术社区戒毒电子系统。在此基础上,我们提出针对MA依赖建立基于评估的精准综合干预模式,即全病程(whole course)、精准化(accurate)、持续的(repeatedly)、基于临床评估的(measurement-based)综合干预模式,简称WARM模式。WARM模式从MA依赖者不同阶段面临的问题入手,致力于实现MA患者的多维度康复,并将进一步探索人工智能辅助的新布局。
简介:摘要肺段切除术是指根据肺脏解剖结构游离支气管肺段至肺门,离断肺段支气管及血管后所进行的解剖性肺切除。随着病灶定位、肺段交界平面确定等技术的发展,在原发性肺癌、转移性肺癌和肺部其他良性病变治疗中逐渐被应用。各种因素影响下,肺段切除术后患者肺功能出现不同程度的降低,最终将直接影响患者预后和术后生活质量。本文主要针对肺段切除术的技术要点及其对肺功能的影响进行综述。
简介: 【摘 要】目的:分析不同剂量辛伐他汀治疗高血压合并高脂血症的效果及安全性。方法:在 2018年 1月到 2019年 3月选取我院接诊的老年高血压、高脂血症患者 200例作为案例进行研究分析。以随机数字法方式分组。两组患者均应用辛伐他汀进行治疗。常规组在睡前应用低剂量辛伐他汀,实验组在睡前应用高剂量辛伐他汀。总结并对比两组患者的血压、血脂指标以及不良反应发生率。结果:治疗前两组患者的血压指标差异不突出,对比结果无意义( P>0.05)。实验组患者的 24小时平均收缩压显著优于常规组,组间对比结果差异显著,满足统计学意义标准( P<0.05) ;治疗前两组患者的血脂指标差异不突出,对比结果无意義( P>0.05)。实验组患者的各项血脂指标均显著优于常规组,组间对比结果差异显著,满足统计学意义标准( P<0.05) ;两组患者在治疗期间均无严重不良反应,数据无差异( P>0.05)。结论:不同剂量辛伐他汀治疗高血压合并高脂血症的效果差异较大,高剂量( 40mg/次)的用量相对于低剂量( 20mg/次)的用药方式具备更加突出的临床疗效,整体治疗效果突出,值得推广普及。 【关键词】辛伐他汀 ;高血压 ;高脂血症 ;临床疗效 ;安全性 Objective: to analyze the efficacy and safety of different doses of simvastatin in the treatment of hypertension complicated with hyperlipidemia. Methods: from January 2018 to March 2019, 200 elderly patients with hypertension and hyperlipidemia in our hospital were selected as cases for study and analysis. They were grouped by random number method. Both groups were treated with simvastatin. The conventional group was given low-dose simvastatin before going to bed, while the experimental group was given high-dose simvastatin before going to bed. The blood pressure, blood lipid index and incidence of adverse reactions were summarized and compared between the two groups. Results: there was no significant difference in blood pressure index between the two groups before treatment (P > 0.05). The 24-hour mean systolic blood pressure of the experimental group was significantly better than that of the conventional group, and the difference between the two groups was significant (P < 0.05); before treatment, the difference of blood lipid index between the two groups was not prominent, and the comparison result was not significant (P > 0.05). The blood lipid indexes of the experimental group were significantly better than those of the conventional group, and the difference between the two groups was significant (P < 0.05); there was no serious adverse reaction in the two groups during the treatment, and the data had no difference (P > 0.05). Conclusion: the effect of different doses of simvastatin in the treatment of hypertension complicated with hyperlipidemia is quite different. The dosage of high-dose (40mg / time) has more prominent clinical effect than the low-dose (20mg / time), and the overall treatment effect is outstanding, which is worthy of popularization.
简介: 【摘要】目的:本文主要对急性酒精中毒后出现胃粘膜损伤的患者在治疗中应用泮托拉唑治療取得的效果展开探究,了解泮托拉唑对疗效产生的影响。方法:研究的对象为本院 2019年 1月 -2019年 12月期间接受治疗的急性酒精中毒后出现胃粘膜损伤的患者(例数 =50),经回顾性方式对患者展开分组纳入,对照组(例数 =25)在诊疗期间进行西咪替丁治疗,研究组(例数 =25)在诊疗期间接受泮托拉唑治疗,对 2组取得的治疗效果展开组间的分析。结果:研究组经泮托拉唑治疗后总有效率与对照组有差异,两组关于数据差异有统计学意义( P值范围 <0.05)。结论:单一的应用西咪替丁、泮托拉唑治疗在急性酒精中毒治疗中,均可有效改善患者疗效。但相比于单一的西咪替丁治疗,急性酒精中毒患者采用泮托拉唑治疗可有效改善患者的疗效,可值得推广。 【关键词】泮托拉唑 ;急性酒精中毒 ;西咪替丁 ;胃粘膜损伤 [Abstract] Objective: To explore the effect of pantoprazole in the treatment of patients with gastric mucosal injury after acute alcoholism, and to understand the effect of pantoprazole on the curative effect. Methods: Patients with gastric mucosal injury after acute alcoholism treated in our hospital from January 2019 to December 2019 (cases = 50) were enrolled in the study. The patients in the control group (cases = 25) were treated with cimetidine during the diagnosis and treatment, and the patients in the study group (cases = 25) were treated with pantoprazole during the diagnosis and treatment The results were analyzed between groups. Results: after pantoprazole treatment, the total effective rate of the study group was significantly different from that of the control group, and the difference between the two groups was statistically significant (P < 0.05). Conclusion: single application of cimetidine and pantoprazole in the treatment of acute alcoholism can effectively improve the curative effect of patients. However, compared with cimetidine alone, pantoprazole can effectively improve the efficacy of patients with acute alcoholism, which is worthy of promotion.
简介:【摘要】 目的 针对冠心病患者采用瑞舒伐他汀和阿托伐他汀进行治疗,对临床效果进行比较和分析。 方法 纳入病例:128例,病症:冠心病,入组时间:2019年3月-2021年3月,分组方式:电脑等量随机方式,组别:实验及对照,各64例,治疗方式:分别采用瑞舒伐他汀和阿托伐托汀开展治疗,对治疗效果进行比较。结果 组内比较,两组患者的LDL-C、TG、TC相较于治疗前均有所下降,HDL-C指标相较于治疗前有所提高;组间比较,实验组患者LDL-C、TG、TC相较于对照组明显更低,HDL-C水平和治疗有效率显著更高,差异显著,p<0.05。结论 针对冠心病患者采用瑞舒伐他汀和阿伐他汀进行治疗,都具有一定的血脂调节效果,但是瑞舒伐他汀相较于阿伐他汀效果更佳明显,治疗有效率更高。
简介:【摘要】目的 对匹多莫德、地塞米松联合阿奇霉素在支原体肺炎治疗中的应用效果以及对患儿血清炎症因子以及免疫功能的影响展开分析。方法 将我院于2019年9月到2021年3月期间收治的98例支原体肺肺炎患儿作为研究对象,随机分组后观察组与对照组各49例,对照组用地塞米松联合阿奇霉素对患者展开治疗,观察组用匹多莫德、四塞米松联合阿奇霉素对患者展开治疗。结果 观察组治疗后血清炎症因子水平以及CD8+水平明显低于对照组,CD4+以及CD3+水平则明显高于对照组。(P<0.05)结论 用匹多莫德、地塞米松联合阿奇霉素对支原体肺炎患儿展开治疗可有效改善患儿炎症反应,提高患儿免疫功能,进一步优化治疗效果,值得推广。