简介：摘要 目的：分析头孢曲松联合氨苄西林钠舒巴坦钠治疗小儿化脓性脑膜炎效果及不良反应率。方法： 2018年 9月 -2019年 9月收治小兒化脓性脑膜炎患儿 50例，根据治疗方案不同分为两组各 25例，对照组进行头孢曲松治疗，试验组进行头孢曲松联合氨苄西林钠舒巴坦钠治疗，对比两组患儿治疗效果。结果：治疗后，试验组患儿治疗有效率高于对照组患儿，比较差异有统计学意义（ P<0.05）。结论：头孢曲松以及氨苄西林钠舒巴坦钠联合用药用于治疗小儿化脓性脑膜炎效果显著，并且安全性高，值得大力推广。  　　关键词头孢曲松 ;氨苄西林钠舒巴坦钠 ;小儿化脓性脑膜炎 ;治疗有效率 ;不良反应  Objective: to analyze the effect and adverse reaction rate of ceftriaxone combined with ampicillin sodium and sulbactam sodium in the treatment of children with purulent meningitis. Methods: 50 cases of children with purulent meningitis were treated from September 2018 to September 2019, and they were divided into two groups according to different treatment schemes, 25 cases in each group. The control group was treated with ceftriaxone, and the experimental group was treated with ceftriaxone combined with ampicillin sodium and sulbactam sodium. Results: after treatment, the effective rate of the experimental group was higher than that of the control group (P < 0.05). Conclusion: ceftriaxone combined with ampicillin sodium and sulbactam sodium in the treatment of children with purulent meningitis has significant effect and high safety, which is worthy of promotion.

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