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4 个结果
  • 简介:   [摘要 ] 目的 探討复方曲尼司特治疗轻、中度哮喘患者急性发作疗效观察及对炎症细胞因子影响。 方法选取 2019年 2—12月于我院就诊轻、中度哮喘急性发作患者共 108例,按随机数字法,随机分成沙丁胺醇组、复方曲尼司特组、孟鲁司特钠组,每组各 36例,疗程 2周,观察 3组治疗前后临床疗效、肺功能、 FeNO、诱导痰嗜酸性粒细胞百分比、外周血炎症因子等变化情况。结果 肺功能方面,复方曲尼司特组、孟鲁司特钠组 FEV1[( 2.63±0.69) L、( 2.61±0.54) L]、 FVC[( 3.29±0.83) L、( 3.27±0.62) L]较沙丁胺醇组 FEV1( 2.26±0.78) L、 FVC( 2.86±0.81) L改善,差异有统计学意义( F=6.802, P=0.033;F=6.828, P=0.033) ;FeNO下降水平方面,复方曲尼司特组、孟鲁司特钠组 [( 77.24±8.25) ppb、( 76.02±6.98) ppb]下降也显著优于沙丁胺醇组( 80.22±20.41) ppb],下降水平( F=12.856, P=0.002) ;此外,复方曲尼司特组、孟鲁司特钠组在气道高反应性指标如诱导痰嗜酸性粒细胞百分比 [( 8.99±2.85) %、( 8.44±2.43) %]、 IgE[( 95.10±114.14) IU/mL、( 93.61±62.63) IU/mL]水平改善方面也显著优于沙丁胺醇组嗜酸性粒细胞百分比( 11.37±1.63) %及 IgE( 216.43±205.85) IU/mL下降比例( F=15.734, P=0.001;F=6.596, P=0.037)。结论 复方曲尼司治疗轻、中度支气管哮喘急性发作疗效可靠,值得临床推广使用。     [关键词 ] 轻中度哮喘 ;复方曲尼司特 ;肺功能 ;FeNO;炎症因子 

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  • 简介:【摘要】目的研究不同药物联合卡络磺钠对支气管扩张伴咯血进行治疗效果分析。方法采用分组对照方法进行研究,所有研究对象为我院在 2018年 12月到 2020年 3月收治支气管伴咯血患者,本研究选择其中 45例患者作为垂体后叶素联合组,主要选择采用垂体后叶素联合卡络磺钠治疗,同时选择同期 45例患者作为酚妥拉明联合组,选择酚妥拉明联合卡络磺钠进行治疗,对两组患者治疗效果进行比较,并作出评价。结果对于两组患者治疗总有效率情况进行评价和比较,酚妥拉明联合组治疗总有效率为 95.56%( 43/45),垂体后叶素联合组治疗总有效率为 84.44%( 38/45),两组进行比较, P< 0.05,差异具有统计学意义;对于两组患者治疗不良反应发生率进行比较,垂体后叶素联合组不良反应发生率为 11.11%( 5/45),酚妥拉明联合组不良反应发生率为 13.33%( 6/45),两组研究对象对于不良反应发生率方面没有明显差异, P> 0.05,不具有统计学意义。结论对于支气管扩张伴咯血患者在进行治疗过程中,为患者选择药物酚妥拉明联合卡络磺钠进行治疗可以取得良好治疗效果,并且具有一定安全性,值得推广。

  • 标签: 垂体后叶素 酚妥拉明 支气管扩张
  • 简介:  【摘 要】目的:分析尿激酶注射液联合序贯抗凝疗法治疗老年肺栓塞临床效果。方法:研究阶段为 2017年 3月~ 2019年 3月,共纳入研究对象 73例,均为老年肺栓塞患者,电脑随机分组,对照组采用低分子肝素钙治疗,观察组采取尿激酶注射液联合序贯抗凝疗法治疗治疗,比较两组临床效果。结果:对照组临床总有效 72.22%低于观察组临床总有效 94.59%,差异有统计学意义( P<0.05)。结论:针对老年肺栓塞患者采用尿激酶注射液联合序贯抗凝疗法治疗可获得良好临床疗效,值得临床应用与推广。    【关键词】尿激酶注射液 ;序贯抗凝疗法 ;老年肺栓塞 ;效果    [Abstract] Objective: to analyze the clinical effect of urokinase injection combined with sequential anticoagulation in the treatment of pulmonary embolism in the elderly. Methods: the study period was from March 2017 to March 2019. 73 patients were randomly divided into two groups. The control group was treated with low molecular weight heparin calcium. The observation group was treated with urokinase injection combined with sequential anticoagulation therapy. Results: the total effective rate of the control group was 72.22%, which was lower than that of the observation group (94.59%) (P < 0.05). Conclusion: urokinase injection combined with sequential anticoagulant therapy can achieve good clinical effect in the elderly patients with pulmonary embolism, and it is worthy of clinical application and promotion.

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  • 简介:  【摘要】目的:探讨老年哮喘急性发作患者采用硫酸沙丁胺醇气雾剂吸入与茶碱控释片进行治疗临床效果。方法:从我院在 2018年 6月 -2020年 5月期间诊治老年哮喘急性发作患者当中选择 60例作为研究对象,随机对患者进行编号, 1-60号,其中奇数号为对照组, 30例,实施硫酸沙丁胺醇气雾剂吸入治疗,偶数号为观察组, 30例,在对照组治疗基础上增加茶碱控释片治疗。结果:治疗前两组患者肺功能相关指标相比无显著差异( P>0.05),治疗后两组都所有变化,且观察组变化更加明显( P<0.05);观察组有效率为 93.33%,对照组有效率为 76.67%,两组对比差异有统计学意义( P0.05),没有统计学意义。结论:联合采用硫酸沙丁胺醇气雾剂吸入与茶碱控释片治疗老年哮喘急性发作患者,可以有效改善患者症状,提高患者肺部功能,值得临床推广。    【关键词】硫酸沙丁胺醇气雾剂;茶碱控释片;急诊;老年哮喘急性发作  Objective: To investigate the clinical effect of salbutamol sulfate aerosol inhalation and theophylline controlled-release tablets in the treatment of elderly patients with acute asthma attack. Methods: from June 2018 to may 2020, 60 patients with acute attack of asthma in the elderly were selected as the study object. Patients were randomly numbered, No. 1-60, including the odd number as the control group, 30 patients, who were treated with salbutamol sulfate aerosol inhalation, even number as the observation group, 30 patients, who were treated with theophylline controlled-release tablets on the basis of the control group. Results: there was no significant difference between the two groups before treatment (P > 0.05). After treatment, there were all changes in the two groups, and the change in the observation group was more obvious (P < 0.05); the effective rate of the observation group was 93.33%, and the effective rate of the control group was 76.67%. The difference between the two groups was statistically significant (P0.05), no statistical significance. Conclusion: the combination of salbutamol sulfate aerosol inhalation and theophylline controlled-release tablets can effectively improve the symptoms of the elderly patients with acute asthma attack, improve the lung function of the patients, and is worthy of clinical promotion.

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