简介：　　【摘要】目的 探究解磷定注射液联合早期血液灌流急诊治疗有机磷农药中毒的效果。方法 选择我院急诊科自 2017年 1月至 2019年 12月收治的 65例有机磷农药中毒患者作為研究对象，随机将其分成对照组（ 32例）和研究组（ 33例），对照组采用解磷定注射液治疗，研究组采用解磷定注射液联合早期血液灌流治疗，对比两组患者自主呼吸恢复时间、意识恢复时间、胆碱酯酶活力恢复时间及抢救成功率。结果 研究组患者自主呼吸恢复时间（ 3.13±0.18） d、意识恢复时间（ 4.26±0.37） d、胆碱酯酶活力恢复时间（ 4.19±0.36） d均显著短于对照组（ 5.21±0.46） d、（ 12.84±2.15） d、（ 13.05±2.21） d，研究组患者抢救成功率 96.97%显著高于对照组 81.25%，两组对比，差异有统计学意义（ P<0.05）。结论 对急诊有机磷农药中毒患者采用解磷定注射液联合早期血液灌流治疗，不仅能有效提高患者抢救成功率，还能缩短其预后时间。  　　【关键词】解磷定注射液 ;早期血液灌流 ;有机磷农药中毒  [Abstract] Objective To explore the effect of jiephosphoridine injection combined with early hemoperfusion in the emergency treatment of organophosphorus pesticide poisoning. method 65 patients with organophosphorus pesticide poisoning admitted to the emergency department of our hospital from January 2017 to December 2019 were randomly divided into the control group (32 cases) and the study group (33 cases). The control group was treated with antiphosphoridine injection, and the study group was treated with antiphosphoridine injection combined with early hemoperfusion. The recovery time of spontaneous respiration and consciousness of the two groups were compared , cholinesterase activity recovery time and rescue success rate. result The recovery time of spontaneous respiration (3.13 ± 0.18) d, consciousness (4.26 ± 0.37) D and cholinesterase activity (4.19 ± 0.36) d in the study group were significantly shorter than those in the control group (5.21 ± 0.46) d, (12.84 ± 2.15) D and (13.05 ± 2.21) d. The Rescue power in the study group was 96.97% higher than that in the control group (81.25%). The difference was statistically significant (P < 0.05) 。 Conclusion the combination of jiephosphoridine injection and early hemoperfusion can not only improve the success rate of rescue, but also shorten the time of prognosis.