简介：摘要目的对比研究消化性溃疡疾病患者采用奥美拉唑和泮托拉唑两种药物实施治疗的临床效果。方法选择过去我院收治的112例消化性溃疡疾病患者，将其以随机分组的方式分成对照组和治疗组，平均每组56例。对照组采用奥美拉唑进行治疗；治疗组采用泮托拉唑进行治疗。对比两组患者药物导致不良反应例数、消化性溃疡症状消失时间和用药总时间、消化性溃疡病情药物控制总有效率。结果治疗组患者药物导致不良反应仅有2例，少于对照组的10例，差异显著（P＜0.05）；消化性溃疡症状消失时间和用药总时间短于对照组，组间数据差异显著（P＜0.05）；消化性溃疡病情药物控制总有效率为91.1%，对照组为69.7%，组间差异显著（P＜0.05）。结论消化性溃疡疾病患者采用泮托拉唑实施治疗，能够减少药物导致的不良反应，缩短临床用药时间，在短时间内控制症状，使疾病的治疗效果提高。

简介：　　【摘要】目的：本文主要对急性酒精中毒后出现胃粘膜损伤的患者在治疗中应用泮托拉唑治療取得的效果展开探究，了解泮托拉唑对疗效产生的影响。方法：研究的对象为本院 2019年 1月 -2019年 12月期间接受治疗的急性酒精中毒后出现胃粘膜损伤的患者（例数 =50），经回顾性方式对患者展开分组纳入，对照组（例数 =25）在诊疗期间进行西咪替丁治疗，研究组（例数 =25）在诊疗期间接受泮托拉唑治疗，对 2组取得的治疗效果展开组间的分析。结果：研究组经泮托拉唑治疗后总有效率与对照组有差异，两组关于数据差异有统计学意义（ P值范围 <0.05）。结论：单一的应用西咪替丁、泮托拉唑治疗在急性酒精中毒治疗中，均可有效改善患者疗效。但相比于单一的西咪替丁治疗，急性酒精中毒患者采用泮托拉唑治疗可有效改善患者的疗效，可值得推广。  　　【关键词】泮托拉唑 ;急性酒精中毒 ;西咪替丁 ;胃粘膜损伤  　 [Abstract] Objective: To explore the effect of pantoprazole in the treatment of patients with gastric mucosal injury after acute alcoholism, and to understand the effect of pantoprazole on the curative effect. Methods: Patients with gastric mucosal injury after acute alcoholism treated in our hospital from January 2019 to December 2019 (cases = 50) were enrolled in the study. The patients in the control group (cases = 25) were treated with cimetidine during the diagnosis and treatment, and the patients in the study group (cases = 25) were treated with pantoprazole during the diagnosis and treatment The results were analyzed between groups. Results: after pantoprazole treatment, the total effective rate of the study group was significantly different from that of the control group, and the difference between the two groups was statistically significant (P < 0.05). Conclusion: single application of cimetidine and pantoprazole in the treatment of acute alcoholism can effectively improve the curative effect of patients. However, compared with cimetidine alone, pantoprazole can effectively improve the efficacy of patients with acute alcoholism, which is worthy of promotion.