摘要
【摘 要】 目的：探讨抗结核药物联合胸腺肽治疗老年结核性胸膜炎的临床效果。方法：选取 2018年 1月至 2020年 1月收治的 98例老年结核性胸膜炎患者，按照随机数字表达法分为观察组与参考组，各为 49例。两组均接受常规抗结核药物治疗，观察组加用胸腺肽治疗，观察两组治疗效果。结果：观察组治疗总有效率、胸腔积液完全吸收率均明显大于参考组（ P<0.05） ;观察组血 -干扰素（ INF-）、白细胞介素 -2（ IL-2）、白细胞介素 -4（ IL-4）、白细胞介素 -8（ IL-8）水平均明显优于参考组（ P<0.05）。结论：抗结核药物联合胸腺肽治疗老年结核性胸膜炎可提高患者免疫力，治疗效果确切，可作为安全有效的联合治疗方案推广。
【关键词】 抗结核药物 ;胸腺肽 ;老年结核性胸膜炎
Objective: To investigate the clinical effect of antituberculosis drugs combined with thymosin in the treatment of senile tuberculous pleurisy. Methods: 98 elderly patients with tuberculous pleurisy from January 2018 to January 2020 were selected and randomly divided into observation group and reference group, with 49 cases in each group. Both groups were treated with conventional anti tuberculosis drugs, and the observation group was treated with thymosin. Results: the total effective rate and pleural effusion complete absorption rate of the observation group were significantly higher than those of the reference group (P < 0.05); the levels of serum interferon (INF -), interleukin-2 (IL-2), interleukin-4 (IL-4) and interleukin-8 (IL-8) in the observation group were significantly better than those in the reference group (P < 0.05). Conclusion: antituberculosis drugs combined with thymosin in the treatment of elderly patients with tuberculous pleurisy can improve the immunity of patients with definite therapeutic effect, which can be promoted as a safe and effective combined treatment scheme.
出版日期
2020年09月12日（中国期刊网平台首次上网日期，不代表论文的发表时间）
