奥卡西平治疗颅脑损伤后癫痫62例临床观察

颅脑创伤后癫痫 奥卡西平 视频脑电图 疗效AbstractobjectiveTO investigate the effects and safety of oxcarbazepine monotherapy or adding in the treatment of post-traumatic epilepsy（PTE）.MethodsSelected 62 patients According to the diagnostic standard were treatmented by oxcarbazepine single or add-on therapymaintenance dose of 600mg ~ 1500mg.The result of video EEG，seizure condition，function of liver and kidney，electrolyte and blood routine werecomparatively analyzed after 1 year treatment.ResultsAfter treatment，the total effective rate was 85.48%，of which 41 cases were cured（66.13%），effective in 12 cases（19.35%），invalid in 9 cases（14.52%）.The abnormal degree of VEEG and abnormal rate of Before and after the treatment werecompared，there are significant statistical differences（P< 0.05）.Liver and kidney function before and after treatment，the abnormal rate of blood testresults had no significant difference.ConclusionOxcarbazepine monotherapy or add-on therapy of PTE，clinical curative effect is reliable，safe