摘要
Studieshavebeencarriedouttotesttheassumptionthattheprimaryphotoreceptorsfortheradioprotectiveactionof633nmlaserradiationarethecytochrome-c-oxidases.Todothis,thedevicewascreatedforradiationprotectionofbiologicalobjectsbasedonlasermodulewithawavelengthof532nm.Experimentsconductedonmurinefibroblastcellsshowedthattheradioprotectioneffectoflaserirradiationwasobservedinthedoseintervalabout0.4-0.85mJ/cm2.Maximumradioprotectioneffectisobservedatlaserradiationenergydensity~0.56mJ/cm2.ThedeterminationofthecellsurvivalwiththeautomaticcounterСТ20aftertheactionoftheionizingandcombinedirradiationshowedthatradioprotectiveactionofthelaserradiationwiththewavelengthof533nm,aswellastheradiationwiththewavelengthof633nm,istransferredbythemechanismofthe“bystandereffect”.Inaddition,itwasfoundthatradioprotectioneffectoflaserirradiationobservedonthecriterionofnumberofsurvivingsinglecells,comparedwithcellsexposedto?-radiationLaserirradiation,produceseffectiveradioprotectingactionalsoonthecriterionofgrowncellcolonies.Thevalueofthedosemodificationfactor(DMF)calculatedon50%cellsurvival(LD50)isequalto1.4.Theresultssuggestthatinthecaseofradioprotectiveactionofsmalldosesoflaserradiationwithawavelengthof633nm,aswellas532nmprimaryphotoreceptorsisthecytochrome-c-oxidases.
出版日期
2018年02月12日（中国期刊网平台首次上网日期，不代表论文的发表时间）
