摘要
Genomeassemblyisaprerequisitestepforanalyzingnextgenerationsequencingdataandalsofarfrombeingsolved.Manyassemblytoolshavebeenproposedandusedextensively.Majorityofthemaimtoassemblesequencingreadsintocontigs;however,wefocusontheassemblyofcontigsintoscaffoldsinthispaper.Thisiscalledscaffolding,whichestimatestherelativeorderofthecontigsaswellasthesizeofthegapsbetweenthesecontigs.Pheromonetrail-basedgeneticalgorithm(PGA)waspreviouslyproposedandhaddecentperformanceaccordingtotheirpaper.Fromourpreviousstudy,wefoundthatfamilycompetitionmechanismingeneticalgorithmisabletofurtherimprovetheresults.Therefore,weproposefamilycompetitionpheromonegeneticalgorithm(FCPGA)anddemonstratetheimprovementoverPGA.
出版日期
2014年04月14日(中国期刊网平台首次上网日期,不代表论文的发表时间)